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Kim Berube's avatar

Your work has been so influential to me. I plan to read every article you’ve written!

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Moro Balakrishnan's avatar

More on your views. If overflow (of glucose) in the cells is the reason for insulin unable to push fresh glucose from the blood into the cells, how does this overflow come about ? That becomes the primary cause of insulin resistance, the how part of it. Perhaps mitochondrial dysfunction, not efficiently converting glucose into energy. And what if this dysfunction itself is brought about by inflammation or oxidative distress or free radicals. This is where the borderline between cause and effect could merge. I mean the traditionally regarded effects like these three are the cause themselves. We have seen this in Covid, especially the second auto immune phase with an inflammation overdrive. Mitochondrial functional slump is also ascribed to the various presentations of long Covid or even long vax (PVS). And some of these symptoms, like tiredness etc, are also manifestations in some severe T2d cases. This clearly brings us to a premise I have been conveying in many comments - that diseases often share presentations, manifestations, often pathways in their progress and reign. And the need to look for repurposed drugs. Often they can boost the performance of supplements and dietary options.

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